Inget id har skickats in.

Karl-Fredrik Norrback

Contact Information

vCard vcard

Position:

Forskare

personbild

Works at:

Clinical Sciences

Department:

Psykiatri

Address:

Umeå universitet, Psykiatri
SE-901 85 Umeå
Sverige

Visiting Address:

23, våning 5, Psykiatriska kliniken

Email:

karl-fredrik.norrback@umu.seEmail 1

karl-fredrik.norrback@psychiat.umu.seEmail 2

Lync:

Get in touch via Lync

Web Page:

http://www.clinsci.umu.se/enheter/psychiat/personal/Karlfredrik-norrback/ Web Page
http://www.clinsci.umu.se/english/units/psychiat/staff/karlfredrik-norrback/ Web Page

Background

I was born in 1972. I got my PhD in Medicine at Umeå University, department of Medical Biosciences with the dissertation “Telomeres and telomerase in normal and malignant hematopoietic cells” in 2000. I received my MD in 2004, Umeå University and I have since then performed research at the department of Clinical Sciences, Psychiatry. I became an associate professor of Experimental Psychiatry in 2013.

Research partners
My main collaborator has been Professor Rolf Adolfsson (the psychiatry unit). Other important collaborators throughout my research; Professor Göran Roos (Umeå University), Professor Lars-Göran Nilsson (Stockholm University) and Professor Jurgen Del-Favero (Antwerp University).

Three major research areas of mine
1. Telomere biology

Research on telomeres which are repetitive DNA-sequences capping the chromosomes was awarded the Nobel Prize in 2009. Telomeres are believed to influence the aging process and to provide information pertaining to the biological age. Most recently, I have been investigating the biomarker value of the telomere length pertaining to structural and functional measures of the brain. See also the doctoral dissertation “Telomeres and the brain” (2011) by Mikael Wikgren (I was the main supervisor).

2. Causes and effects of stress and stress-dysregulation.
The research is focused at understanding the causes and effects of stress and stress-dysregulation in the general population and in affective disorders. We have a particular interest in investigating one of the body’s most central stress-coping systems; the HPA-axis and its effector molecule cortisol. Martin Maripuu is currently working on his PhD-thesis (I am the main supervisor) within the project.

3. Psychosomatics
One psychosomatic condition studied is IBS which shows comorbidity with affective disorders, stress and inflammation. The pathophysiology of IBS is however largely unknown. We also study chronic pain from which many suffer often without medical doctors being able to identify specific causes. We investigate the role of stress- and mood-dysregulation for the etiology and the expression of these conditions. See also the doctoral dissertation “The emotional motor system and gastrointestinal symptoms” (2008) by Pontus Karling (I was co-supervisor).

Teaching
I have taught on a diverse number of subjects within the following university programs at Umeå University, e.g.: the programs of medicin, dentistry, biomedicine, science in environmental health, speech and language pathology. I have tutored PhD-students since 2005.

Publications

Author

Title

Year sorteringsordning

Fulltext

Maripuu, Martin
Wikgren, Mikael
Karling, Pontus; et al.

Hyper- and hypocortisolism in bipolar disorder: A beneficial influence of lithium on the HPA-axis?
Journal of Affective Disorders, 213: 161-167

2017

-

Maripuu, Martin
Wikgren, Mikael
Karling, Pontus; et al.

Relative hypocortisolism is associated with obesity and the metabolic syndrome in recurrent affective disorders
Journal of Affective Disorders, 204: 187-196

2016

-

Karling, Pontus
Maripuu, Martin
Wikgren, Mikael; et al.

Association between gastrointestinal symptoms and affectivity in patients with bipolar disorder
World Journal of Gastroenterology, 22(38): 8540-8548

2016

Download

Karling, Pontus
Wikgren, Mikael
Adolfsson, Rolf; et al.

Hypothalamus-Pituitary-Adrenal Axis Hypersuppression Is Associated with Gastrointestinal Symptoms in Major Depression
Journal of neurogastroenterology and motility, 22(2): 292-303

2016

-

Maripuu, Martin
Wikgren, Mikael
Karling, Pontus; et al.

Relative Hypo- and Hypercortisolism are Both Associated with Depression and Lower Quality of Life in Bipolar Disorder
Journal of Psychosomatic Research, 85: 73-74

2016

-

Forero, Diego A.
Herteleer, Liesbet
De Zutter, Sonia; et al.

A network of synaptic genes associated with schizophrenia and bipolar disorder
Schizophrenia Research, 17(1-3): 68-74

2016

-

Maripuu, Martin Peter
Wikgren, Mikael
Karling, Pontus; et al.

Relative hypocortisolism is associated with obesity and the metabolic syndrome in recurrent affective disorders
Psychoneuroendocrinology, 71: 64-65

2016

-

Wikgren, Mikael
Karlsson, Thomas
Söderlund, Hedvig; et al.

Shorter telomere length is linked to brain atrophy and white matter hyperintensities
Age and Ageing, 43(2): 212-217

2014

-

Maripuu, Martin
Wikgren, Mikael
Karling, Pontus; et al.

Relative Hypo-and Hypercortisolism Are Both Associated with Depression and Lower Quality of Life in Bipolar Disorder: A Cross-Sectional Study
PLoS ONE, 9(6)

2014

Download

Wikgren, Mikael
Karlsson, Thomas
Lind, Johanna; et al.

Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects
PLoS ONE, 7(4): e34292-

2012

Download

Background

I was born in 1972. I got my PhD in Medicine at Umeå University, department of Medical Biosciences with the dissertation “Telomeres and telomerase in normal and malignant hematopoietic cells” in 2000. I received my MD in 2004, Umeå University and I have since then performed research at the department of Clinical Sciences, Psychiatry. I became an associate professor of Experimental Psychiatry in 2013.

Research partners
My main collaborator has been Professor Rolf Adolfsson (the psychiatry unit). Other important collaborators throughout my research; Professor Göran Roos (Umeå University), Professor Lars-Göran Nilsson (Stockholm University) and Professor Jurgen Del-Favero (Antwerp University).

Three major research areas of mine
1. Telomere biology

Research on telomeres which are repetitive DNA-sequences capping the chromosomes was awarded the Nobel Prize in 2009. Telomeres are believed to influence the aging process and to provide information pertaining to the biological age. Most recently, I have been investigating the biomarker value of the telomere length pertaining to structural and functional measures of the brain. See also the doctoral dissertation “Telomeres and the brain” (2011) by Mikael Wikgren (I was the main supervisor).

2. Causes and effects of stress and stress-dysregulation.
The research is focused at understanding the causes and effects of stress and stress-dysregulation in the general population and in affective disorders. We have a particular interest in investigating one of the body’s most central stress-coping systems; the HPA-axis and its effector molecule cortisol. Martin Maripuu is currently working on his PhD-thesis (I am the main supervisor) within the project.

3. Psychosomatics
One psychosomatic condition studied is IBS which shows comorbidity with affective disorders, stress and inflammation. The pathophysiology of IBS is however largely unknown. We also study chronic pain from which many suffer often without medical doctors being able to identify specific causes. We investigate the role of stress- and mood-dysregulation for the etiology and the expression of these conditions. See also the doctoral dissertation “The emotional motor system and gastrointestinal symptoms” (2008) by Pontus Karling (I was co-supervisor).

Teaching
I have taught on a diverse number of subjects within the following university programs at Umeå University, e.g.: the programs of medicin, dentistry, biomedicine, science in environmental health, speech and language pathology. I have tutored PhD-students since 2005.


Page Editor: Helena Harding

Print page